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peprotech 315-05peprotech Recombinant Murine IFN-γ细胞因子

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上海力敏实业有限公司
2015-12-23 08:23:53
上海市
1057
13634112423QQ:2856177234

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【简单介绍】

Synonyms:

Immune Interferon, type II interferon, T cell interferon, MAF

此类产品还有重组人的IFN

【详细说明】

Catalog Number:

315-05

Synonyms:

Immune Interferon, type II interferon, T cell interferon, MAF

Description:

IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper （CD4+） cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues.

AA Sequence:

MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC

Source:

E.coli

Purity:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED₅₀ is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10⁶ units/mg.

Cross Reactivity:

Rabbit, Rat, Mouse, Mouse + Chicken, Human, Cow, Bacteria, N/A, Mouse + Parasite

Research Interests:

	AIDS / HIV		Angiogenesis/ Cardiovascular
	Cancer		Diabetes / Weight Regulation
	Immune System		Neurobiology
	Stem Cells & Differentiation		Allergy
	Transplantation

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peprotech 315-05peprotech Recombinant Murine IFN-γ细胞因子

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